MYO1E-GPR176 Fusion FISH Probe
The MYO1E-GPR176 Fusion FISH Probe is used to confirm a fusion of the MYO1E and GPR176 genes. The fusion of the MYO1E and GPR176 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYO1E-GPR176-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-RERE | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-REOR | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-REGO | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-REGR | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-REAQ | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-ORRE | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-OROR | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-ORGO | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-GORE | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-GOOR | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-GOGO | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-GOGR | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-GRRE | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-GROR | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-GRGO | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-GRGR | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-AQRE | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-AQOR | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-AQGO | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-AQGR | 20 (40 μL) | 200 μL |
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| MYO1E-GPR176-20-AQAQ | 20 (40 μL) | 200 μL |
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MYO1E Gene Summary
This gene encodes a member of the nonmuscle class I myosins which are a subgroup of the unconventional myosin protein family. The unconventional myosin proteins function as actin-based molecular motors. Class I myosins are characterized by a head (motor) domain, a regulatory domain and a either a short or long tail domain. Among the class I myosins, this protein is distinguished by a long tail domain that is involved in crosslinking actin filaments. This protein localizes to the cytoplasm and may be involved in intracellular movement and membrane trafficking. Mutations in this gene are the cause of focal segmental glomerulosclerosis-6. This gene has been referred to as myosin IC in the literature but is distinct from the myosin IC gene located on chromosome 17. [provided by RefSeq, Jan 2012]
Gene Name: Myosin IE
Chromosome: CHR15: 59428562 -59665071
Locus: 15q22.2
GPR176 Gene Summary
Members of the G protein-coupled receptor family, such as GPR176, are cell surface receptors involved in responses to hormones, growth factors, and neurotransmitters (Hata et al., 1995 [PubMed 7893747]).[supplied by OMIM, Jul 2008]
Gene Name: G Protein-coupled Receptor 176
Chromosome: CHR15: 40092930 -40213093
Locus: 15q14-q15.1
Gene Diseases
The MYO1E GPR176 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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