MYO1C-SMTNL2 Fusion FISH Probe
The MYO1C-SMTNL2 Fusion FISH Probe is used to confirm a fusion of the MYO1C and SMTNL2 genes. The fusion of the MYO1C and SMTNL2 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYO1C-SMTNL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-RERE | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-REOR | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-REGO | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-REGR | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-REAQ | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-ORRE | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-OROR | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-ORGO | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-GORE | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-GOOR | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-GOGO | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-GOGR | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-GRRE | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-GROR | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-GRGO | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-GRGR | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-AQRE | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-AQOR | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-AQGO | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-AQGR | 20 (40 μL) | 200 μL |
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| MYO1C-SMTNL2-20-AQAQ | 20 (40 μL) | 200 μL |
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MYO1C Gene Summary
This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19. [provided by RefSeq, Jul 2008]
Gene Name: Myosin IC
Chromosome: CHR17: 1367479 -1396001
Locus: 17p13.3
SMTNL2 Gene Summary
The Smoothelin Like 2 (SMTNL2) gene is located on chr17 :4487275-4511614 at 17p13.2.
Gene Name: Smoothelin Like 2
Chromosome: CHR17: 4487275 -4511614
Locus: 17p13.2
Gene Diseases
The MYO1C SMTNL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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