MYO1B-STAT4 Fusion FISH Probe
The MYO1B-STAT4 Fusion FISH Probe is used to confirm a fusion of the MYO1B and STAT4 genes. The fusion of the MYO1B and STAT4 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYO1B-STAT4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-RERE | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-REOR | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-REGO | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-REGR | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-REAQ | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-ORRE | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-OROR | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-ORGO | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-GORE | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-GOOR | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-GOGO | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-GOGR | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-GRRE | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-GROR | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-GRGO | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-GRGR | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-AQRE | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-AQOR | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-AQGO | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-AQGR | 20 (40 μL) | 200 μL |
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| MYO1B-STAT4-20-AQAQ | 20 (40 μL) | 200 μL |
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MYO1B Gene Summary
The Myosin IB (MYO1B) gene is located on chr2 :192110106-192290115 at 2q32.3.
Gene Name: Myosin IB
Chromosome: CHR2: 192110106 -192290115
Locus: 2q32.3
STAT4 Gene Summary
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
Gene Name: Signal Transducer And Activator Of Transcription 4
Chromosome: CHR2: 191894301 -192016322
Locus: 2q32.2-q32.3
Gene Diseases
The MYO1B STAT4 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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