MYO1B-GLS Fusion FISH Probe
The MYO1B-GLS Fusion FISH Probe is used to confirm a fusion of the MYO1B and GLS genes. The fusion of the MYO1B and GLS genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYO1B-GLS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-RERE | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-REOR | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-REGO | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-REGR | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-REAQ | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-ORRE | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-OROR | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-ORGO | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-GORE | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-GOOR | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-GOGO | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-GOGR | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-GRRE | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-GROR | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-GRGO | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-GRGR | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-AQRE | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-AQOR | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-AQGO | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-AQGR | 20 (40 μL) | 200 μL |
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| MYO1B-GLS-20-AQAQ | 20 (40 μL) | 200 μL |
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GLS Gene Summary
This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Gene Name: Glutaminase
Chromosome: CHR2: 191745546 -191829776
Locus: 2q32.2
MYO1B Gene Summary
The Myosin IB (MYO1B) gene is located on chr2 :192110106-192290115 at 2q32.3.
Gene Name: Myosin IB
Chromosome: CHR2: 192110106 -192290115
Locus: 2q32.3
Gene Diseases
The MYO1B GLS Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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