MYO18A-RNF135 Fusion FISH Probe
The MYO18A-RNF135 Fusion FISH Probe is used to confirm a fusion of the MYO18A and RNF135 genes. The fusion of the MYO18A and RNF135 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYO18A-RNF135-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-RERE | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-REOR | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-REGO | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-REGR | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-REAQ | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-ORRE | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-OROR | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-ORGO | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-GORE | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-GOOR | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-GOGO | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-GOGR | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-GRRE | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-GROR | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-GRGO | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-GRGR | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-AQRE | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-AQOR | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-AQGO | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-AQGR | 20 (40 μL) | 200 μL |
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| MYO18A-RNF135-20-AQAQ | 20 (40 μL) | 200 μL |
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RNF135 Gene Summary
The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Name: Ring Finger Protein 135
Chromosome: CHR17: 29297955 -29326929
Locus: 17q11.2
MYO18A Gene Summary
The protein encoded by this gene can bind GOLPH3, linking the Golgi to the cytoskeleton and influencing Golgi membrane trafficking. The encoded protein is also part of a complex that assembles lamellar actomyosin bundles and may be required for cell migration. [provided by RefSeq, Oct 2016]
Gene Name: Myosin XVIIIA
Chromosome: CHR17: 27400527 -27507407
Locus: 17q11.2
Gene Diseases
The MYO18A RNF135 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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