MYO18A-IGF2 Fusion FISH Probe
The MYO18A-IGF2 Fusion FISH Probe is used to confirm a fusion of the MYO18A and IGF2 genes. The fusion of the MYO18A and IGF2 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYO18A-IGF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-RERE | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-REOR | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-REGO | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-REGR | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-REAQ | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-ORRE | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-OROR | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-ORGO | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-GORE | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-GOOR | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-GOGO | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-GOGR | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-GRRE | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-GROR | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-GRGO | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-GRGR | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-AQRE | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-AQOR | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-AQGO | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-AQGR | 20 (40 μL) | 200 μL |
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| MYO18A-IGF2-20-AQAQ | 20 (40 μL) | 200 μL |
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IGF2 Gene Summary
This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Gene Name: Insulin Like Growth Factor 2
Chromosome: CHR11: 2150346 -2170833
Locus: 11p15.5
MYO18A Gene Summary
The protein encoded by this gene can bind GOLPH3, linking the Golgi to the cytoskeleton and influencing Golgi membrane trafficking. The encoded protein is also part of a complex that assembles lamellar actomyosin bundles and may be required for cell migration. [provided by RefSeq, Oct 2016]
Gene Name: Myosin XVIIIA
Chromosome: CHR17: 27400527 -27507407
Locus: 17q11.2
Gene Diseases
The MYO18A IGF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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