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MYO18A-ALDOB Fusion FISH Probe

The MYO18A-ALDOB Fusion FISH Probe is used to confirm a fusion of the MYO18A and ALDOB genes. The fusion of the MYO18A and ALDOB genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MYO18A-ALDOB-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MYO18A-ALDOB-20-RERE 20 (40 μL) 200 μL
MYO18A-ALDOB-20-REOR 20 (40 μL) 200 μL
MYO18A-ALDOB-20-REGO 20 (40 μL) 200 μL
MYO18A-ALDOB-20-REGR 20 (40 μL) 200 μL
MYO18A-ALDOB-20-REAQ 20 (40 μL) 200 μL
MYO18A-ALDOB-20-ORRE 20 (40 μL) 200 μL
MYO18A-ALDOB-20-OROR 20 (40 μL) 200 μL
MYO18A-ALDOB-20-ORGO 20 (40 μL) 200 μL
MYO18A-ALDOB-20-ORAQ 20 (40 μL) 200 μL
MYO18A-ALDOB-20-GORE 20 (40 μL) 200 μL
MYO18A-ALDOB-20-GOOR 20 (40 μL) 200 μL
MYO18A-ALDOB-20-GOGO 20 (40 μL) 200 μL
MYO18A-ALDOB-20-GOGR 20 (40 μL) 200 μL
MYO18A-ALDOB-20-GOAQ 20 (40 μL) 200 μL
MYO18A-ALDOB-20-GRRE 20 (40 μL) 200 μL
MYO18A-ALDOB-20-GROR 20 (40 μL) 200 μL
MYO18A-ALDOB-20-GRGO 20 (40 μL) 200 μL
MYO18A-ALDOB-20-GRGR 20 (40 μL) 200 μL
MYO18A-ALDOB-20-GRAQ 20 (40 μL) 200 μL
MYO18A-ALDOB-20-AQRE 20 (40 μL) 200 μL
MYO18A-ALDOB-20-AQOR 20 (40 μL) 200 μL
MYO18A-ALDOB-20-AQGO 20 (40 μL) 200 μL
MYO18A-ALDOB-20-AQGR 20 (40 μL) 200 μL
MYO18A-ALDOB-20-AQAQ 20 (40 μL) 200 μL

ALDOB Gene Summary

Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq, Dec 2008]

Gene Name: Aldolase, Fructose-bisphosphate B

Chromosome: CHR9: 104182841 -104198062

Locus: 9q31.1

MYO18A Gene Summary

The protein encoded by this gene can bind GOLPH3, linking the Golgi to the cytoskeleton and influencing Golgi membrane trafficking. The encoded protein is also part of a complex that assembles lamellar actomyosin bundles and may be required for cell migration. [provided by RefSeq, Oct 2016]

Gene Name: Myosin XVIIIA

Chromosome: CHR17: 27400527 -27507407

Locus: 17q11.2

Gene Diseases

The MYO18A ALDOB Fusion has been associated with the following diseases:

Disease Name
Liver Hepatocellular Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.