MYO18A-ALDOB Fusion FISH Probe
The MYO18A-ALDOB Fusion FISH Probe is used to confirm a fusion of the MYO18A and ALDOB genes. The fusion of the MYO18A and ALDOB genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYO18A-ALDOB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-RERE | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-REOR | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-REGO | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-REGR | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-REAQ | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-ORRE | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-OROR | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-ORGO | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-GORE | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-GOOR | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-GOGO | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-GOGR | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-GRRE | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-GROR | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-GRGO | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-GRGR | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-AQRE | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-AQOR | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-AQGO | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-AQGR | 20 (40 μL) | 200 μL |
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| MYO18A-ALDOB-20-AQAQ | 20 (40 μL) | 200 μL |
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ALDOB Gene Summary
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq, Dec 2008]
Gene Name: Aldolase, Fructose-bisphosphate B
Chromosome: CHR9: 104182841 -104198062
Locus: 9q31.1
MYO18A Gene Summary
The protein encoded by this gene can bind GOLPH3, linking the Golgi to the cytoskeleton and influencing Golgi membrane trafficking. The encoded protein is also part of a complex that assembles lamellar actomyosin bundles and may be required for cell migration. [provided by RefSeq, Oct 2016]
Gene Name: Myosin XVIIIA
Chromosome: CHR17: 27400527 -27507407
Locus: 17q11.2
Gene Diseases
The MYO18A ALDOB Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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