MYO10-NPR3 Fusion FISH Probe
The MYO10-NPR3 Fusion FISH Probe is used to confirm a fusion of the MYO10 and NPR3 genes. The fusion of the MYO10 and NPR3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYO10-NPR3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-RERE | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-REOR | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-REGO | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-REGR | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-REAQ | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-ORRE | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-OROR | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-ORGO | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-GORE | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-GOOR | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-GOGO | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-GOGR | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-GRRE | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-GROR | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-GRGO | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-GRGR | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-AQRE | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-AQOR | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-AQGO | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-AQGR | 20 (40 μL) | 200 μL |
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| MYO10-NPR3-20-AQAQ | 20 (40 μL) | 200 μL |
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MYO10 Gene Summary
This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-10 (MYH10). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. This gene functions as an actin-based molecular motor and plays a role in integration of F-actin and microtubule cytoskeletons during meiosis. [provided by RefSeq, Dec 2011]
Gene Name: Myosin X
Chromosome: CHR5: 16662015 -16936385
Locus: 5p15.1
NPR3 Gene Summary
This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
Gene Name: Natriuretic Peptide Receptor 3
Chromosome: CHR5: 32710742 -32791830
Locus: 5p13.3
Gene Diseases
The MYO10 NPR3 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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