MYO10-DNAH5 Fusion FISH Probe
The MYO10-DNAH5 Fusion FISH Probe is used to confirm a fusion of the MYO10 and DNAH5 genes. The fusion of the MYO10 and DNAH5 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYO10-DNAH5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-RERE | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-REOR | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-REGO | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-REGR | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-REAQ | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-ORRE | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-OROR | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-ORGO | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-GORE | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-GOOR | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-GOGO | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-GOGR | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-GRRE | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-GROR | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-GRGO | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-GRGR | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-AQRE | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-AQOR | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-AQGO | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-AQGR | 20 (40 μL) | 200 μL |
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| MYO10-DNAH5-20-AQAQ | 20 (40 μL) | 200 μL |
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DNAH5 Gene Summary
This gene encodes a dynein protein, which is part of a microtubule-associated motor protein complex consisting of heavy, light, and intermediate chains. This protein is an axonemal heavy chain dynein. It functions as a force-generating protein with ATPase activity, whereby the release of ADP is thought to produce the force-producing power stroke. Mutations in this gene cause primary ciliary dyskinesia type 3, as well as Kartagener syndrome, which are both diseases due to ciliary defects. [provided by RefSeq, Oct 2009]
Gene Name: Dynein Axonemal Heavy Chain 5
Chromosome: CHR5: 13690436 -13944589
Locus: 5p15.2
MYO10 Gene Summary
This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-10 (MYH10). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. This gene functions as an actin-based molecular motor and plays a role in integration of F-actin and microtubule cytoskeletons during meiosis. [provided by RefSeq, Dec 2011]
Gene Name: Myosin X
Chromosome: CHR5: 16662015 -16936385
Locus: 5p15.1
Gene Diseases
The MYO10 DNAH5 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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