MYL6-STAT6 Fusion FISH Probe
The MYL6-STAT6 Fusion FISH Probe is used to confirm a fusion of the MYL6 and STAT6 genes. The fusion of the MYL6 and STAT6 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYL6-STAT6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-RERE | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-REOR | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-REGO | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-REGR | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-REAQ | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-ORRE | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-OROR | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-ORGO | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-GORE | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-GOOR | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-GOGO | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-GOGR | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-GRRE | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-GROR | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-GRGO | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-GRGR | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-AQRE | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-AQOR | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-AQGO | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-AQGR | 20 (40 μL) | 200 μL |
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| MYL6-STAT6-20-AQAQ | 20 (40 μL) | 200 μL |
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MYL6 Gene Summary
Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Myosin Light Chain 6
Chromosome: CHR12: 56552044 -56555366
Locus: 12q13.2
STAT6 Gene Summary
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Gene Name: Signal Transducer And Activator Of Transcription 6
Chromosome: CHR12: 57489186 -57505196
Locus: 12q13.3
Gene Diseases
The MYL6 STAT6 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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