MYH9-DDX21 Fusion FISH Probe
The MYH9-DDX21 Fusion FISH Probe is used to confirm a fusion of the MYH9 and DDX21 genes. The fusion of the MYH9 and DDX21 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYH9-DDX21-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-RERE | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-REOR | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-REGO | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-REGR | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-REAQ | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-ORRE | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-OROR | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-ORGO | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-GORE | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-GOOR | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-GOGO | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-GOGR | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-GRRE | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-GROR | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-GRGO | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-GRGR | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-AQRE | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-AQOR | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-AQGO | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-AQGR | 20 (40 μL) | 200 μL |
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| MYH9-DDX21-20-AQAQ | 20 (40 μL) | 200 μL |
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MYH9 Gene Summary
This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq, Dec 2011]
Gene Name: Myosin Heavy Chain 9
Chromosome: CHR22: 36677322 -36784063
Locus: 22q12.3
DDX21 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. [provided by RefSeq, Jul 2008]
Gene Name: DExD-box Helicase 21
Chromosome: CHR10: 70715891 -70744279
Locus: 10q22.1
Gene Diseases
The MYH9 DDX21 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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