MYH9-CD74 Fusion FISH Probe
The MYH9-CD74 Fusion FISH Probe is used to confirm a fusion of the MYH9 and CD74 genes. The fusion of the MYH9 and CD74 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYH9-CD74-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-RERE | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-REOR | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-REGO | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-REGR | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-REAQ | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-ORRE | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-OROR | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-ORGO | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-GORE | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-GOOR | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-GOGO | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-GOGR | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-GRRE | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-GROR | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-GRGO | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-GRGR | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-AQRE | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-AQOR | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-AQGO | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-AQGR | 20 (40 μL) | 200 μL |
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| MYH9-CD74-20-AQAQ | 20 (40 μL) | 200 μL |
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CD74 Gene Summary
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Gene Name: CD74 Molecule
Chromosome: CHR5: 149781199 -149792499
Locus: 5q33.1
MYH9 Gene Summary
This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq, Dec 2011]
Gene Name: Myosin Heavy Chain 9
Chromosome: CHR22: 36677322 -36784063
Locus: 22q12.3
Gene Diseases
The MYH9 CD74 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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