MYH9-BIRC6 Fusion FISH Probe
The MYH9-BIRC6 Fusion FISH Probe is used to confirm a fusion of the MYH9 and BIRC6 genes. The fusion of the MYH9 and BIRC6 genes has been associated with Thyroid Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYH9-BIRC6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-RERE | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-REOR | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-REGO | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-REGR | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-REAQ | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-ORRE | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-OROR | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-ORGO | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-GORE | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-GOOR | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-GOGO | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-GOGR | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-GRRE | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-GROR | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-GRGO | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-GRGR | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-AQRE | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-AQOR | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-AQGO | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-AQGR | 20 (40 μL) | 200 μL |
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| MYH9-BIRC6-20-AQAQ | 20 (40 μL) | 200 μL |
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MYH9 Gene Summary
This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq, Dec 2011]
Gene Name: Myosin Heavy Chain 9
Chromosome: CHR22: 36677322 -36784063
Locus: 22q12.3
BIRC6 Gene Summary
This gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein inhibits apoptosis by facilitating the degradation of apoptotic proteins by ubiquitination. [provided by RefSeq, Jul 2008]
Gene Name: Baculoviral IAP Repeat Containing 6
Chromosome: CHR2: 32582095 -32843965
Locus: 2p22.3
Gene Diseases
The MYH9 BIRC6 Fusion has been associated with the following diseases:
| Disease Name |
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| Thyroid Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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