MYH3-CYP3A5 Fusion FISH Probe
The MYH3-CYP3A5 Fusion FISH Probe is used to confirm a fusion of the MYH3 and CYP3A5 genes. The fusion of the MYH3 and CYP3A5 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYH3-CYP3A5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-RERE | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-REOR | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-REGO | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-REGR | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-REAQ | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-ORRE | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-OROR | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-ORGO | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-GORE | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-GOOR | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-GOGO | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-GOGR | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-GRRE | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-GROR | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-GRGO | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-GRGR | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-AQRE | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-AQOR | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-AQGO | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-AQGR | 20 (40 μL) | 200 μL |
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| MYH3-CYP3A5-20-AQAQ | 20 (40 μL) | 200 μL |
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CYP3A5 Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Gene Name: Cytochrome P450 Family 3 Subfamily A Member 5
Chromosome: CHR7: 99245812 -99277621
Locus: 7q22.1
MYH3 Gene Summary
Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. This gene is a member of the MYH family and encodes a protein with an IQ domain and a myosin head-like domain. Mutations in this gene have been associated with two congenital contracture (arthrogryposis) syndromes, Freeman-Sheldon syndrome and Sheldon-Hall syndrome. [provided by RefSeq, Jul 2008]
Gene Name: Myosin Heavy Chain 3
Chromosome: CHR17: 10531842 -10560626
Locus: 17p13.1
Gene Diseases
The MYH3 CYP3A5 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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