MYCBP2-RNF219 Fusion FISH Probe
The MYCBP2-RNF219 Fusion FISH Probe is used to confirm a fusion of the MYCBP2 and RNF219 genes. The fusion of the MYCBP2 and RNF219 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYCBP2-RNF219-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-RERE | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-REOR | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-REGO | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-REGR | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-REAQ | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-ORRE | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-OROR | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-ORGO | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-GORE | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-GOOR | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-GOGO | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-GOGR | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-GRRE | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-GROR | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-GRGO | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-GRGR | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-AQRE | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-AQOR | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-AQGO | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-AQGR | 20 (40 μL) | 200 μL |
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| MYCBP2-RNF219-20-AQAQ | 20 (40 μL) | 200 μL |
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MYCBP2 Gene Summary
This gene encodes an E3 ubiquitin-protein ligase and member of the PHR (Phr1/MYCBP2, highwire and RPM-1) family of proteins. The encoded protein plays a role in axon guidance and synapse formation in the developing nervous system. In mammalian cells, this protein regulates the cAMP and mTOR signaling pathways, and may additionally regulate autophagy. Reduced expression of this gene has been observed in acute lymphoblastic leukemia patients and a mutation in this gene has been identified in patients with a rare inherited vision defect. [provided by RefSeq, Mar 2017]
Gene Name: MYC Binding Protein 2, E3 Ubiquitin Protein Ligase
Chromosome: CHR13: 77618791 -77901177
Locus: 13q22.3
RNF219 Gene Summary
The Ring Finger Protein 219 (RNF219) gene is located on chr13 :79188420-79233314 at 13q31.1.
Gene Name: Ring Finger Protein 219
Chromosome: CHR13: 79188420 -79233314
Locus: 13q31.1
Gene Diseases
The MYCBP2 RNF219 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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