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MYBL2-IFT52 Fusion FISH Probe

The MYBL2-IFT52 Fusion FISH Probe is used to confirm a fusion of the MYBL2 and IFT52 genes. The fusion of the MYBL2 and IFT52 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MYBL2-IFT52-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MYBL2-IFT52-20-RERE 20 (40 μL) 200 μL
MYBL2-IFT52-20-REOR 20 (40 μL) 200 μL
MYBL2-IFT52-20-REGO 20 (40 μL) 200 μL
MYBL2-IFT52-20-REGR 20 (40 μL) 200 μL
MYBL2-IFT52-20-REAQ 20 (40 μL) 200 μL
MYBL2-IFT52-20-ORRE 20 (40 μL) 200 μL
MYBL2-IFT52-20-OROR 20 (40 μL) 200 μL
MYBL2-IFT52-20-ORGO 20 (40 μL) 200 μL
MYBL2-IFT52-20-ORAQ 20 (40 μL) 200 μL
MYBL2-IFT52-20-GORE 20 (40 μL) 200 μL
MYBL2-IFT52-20-GOOR 20 (40 μL) 200 μL
MYBL2-IFT52-20-GOGO 20 (40 μL) 200 μL
MYBL2-IFT52-20-GOGR 20 (40 μL) 200 μL
MYBL2-IFT52-20-GOAQ 20 (40 μL) 200 μL
MYBL2-IFT52-20-GRRE 20 (40 μL) 200 μL
MYBL2-IFT52-20-GROR 20 (40 μL) 200 μL
MYBL2-IFT52-20-GRGO 20 (40 μL) 200 μL
MYBL2-IFT52-20-GRGR 20 (40 μL) 200 μL
MYBL2-IFT52-20-GRAQ 20 (40 μL) 200 μL
MYBL2-IFT52-20-AQRE 20 (40 μL) 200 μL
MYBL2-IFT52-20-AQOR 20 (40 μL) 200 μL
MYBL2-IFT52-20-AQGO 20 (40 μL) 200 μL
MYBL2-IFT52-20-AQGR 20 (40 μL) 200 μL
MYBL2-IFT52-20-AQAQ 20 (40 μL) 200 μL

MYBL2 Gene Summary

The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]

Gene Name: MYB Proto-oncogene Like 2

Chromosome: CHR20: 42295708 -42345122

Locus: 20q13.12

IFT52 Gene Summary

This gene encodes a conserved proline-rich protein that is a component of the intraflagellar transport-B (IFT-B) core complex. The encoded protein is essential for the integrity of the IFT-B core complex, and for biosynthesis and maintenance of cilia. Mutations in this gene are associated with ciliopathy that affects the skeleton. [provided by RefSeq, Oct 2016]

Gene Name: Intraflagellar Transport 52

Chromosome: CHR20: 42219578 -42275862

Locus: 20q13.12

Gene Diseases

The MYBL2 IFT52 Fusion has been associated with the following diseases:

Disease Name
Liver Hepatocellular Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.