MUC4-PCYT1A Fusion FISH Probe
The MUC4-PCYT1A Fusion FISH Probe is used to confirm a fusion of the MUC4 and PCYT1A genes. The fusion of the MUC4 and PCYT1A genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MUC4-PCYT1A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-RERE | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-REOR | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-REGO | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-REGR | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-REAQ | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-ORRE | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-OROR | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-ORGO | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-ORAQ | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-GORE | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-GOOR | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-GOGO | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-GOGR | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-GOAQ | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-GRRE | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-GROR | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-GRGO | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-GRGR | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-GRAQ | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-AQRE | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-AQOR | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-AQGO | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-AQGR | 20 (40 μL) | 200 μL |
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| MUC4-PCYT1A-20-AQAQ | 20 (40 μL) | 200 μL |
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MUC4 Gene Summary
The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of this gene have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. This gene contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats. [provided by RefSeq, Jul 2008]
Gene Name: Mucin 4, Cell Surface Associated
Chromosome: CHR3: 195473637 -195538844
Locus: 3q29
PCYT1A Gene Summary
This gene belongs to the cytidylyltransferase family and is involved in the regulation of phosphatidylcholine biosynthesis. Mutations in this gene are associated with spondylometaphyseal dysplasia with cone-rod dystrophy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015]
Gene Name: Phosphate Cytidylyltransferase 1, Choline, Alpha
Chromosome: CHR3: 195965252 -196014584
Locus: 3q29
Gene Diseases
The MUC4 PCYT1A Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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