MTUS1-ASAH1 Fusion FISH Probe
The MTUS1-ASAH1 Fusion FISH Probe is used to confirm a fusion of the MTUS1 and ASAH1 genes. The fusion of the MTUS1 and ASAH1 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MTUS1-ASAH1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-RERE | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-REOR | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-REGO | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-REGR | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-REAQ | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-ORRE | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-OROR | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-ORGO | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-GORE | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-GOOR | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-GOGO | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-GOGR | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-GRRE | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-GROR | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-GRGO | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-GRGR | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-AQRE | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-AQOR | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-AQGO | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-AQGR | 20 (40 μL) | 200 μL |
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| MTUS1-ASAH1-20-AQAQ | 20 (40 μL) | 200 μL |
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ASAH1 Gene Summary
This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy. [provided by RefSeq, Oct 2015]
Gene Name: N-acylsphingosine Amidohydrolase 1
Chromosome: CHR8: 17913924 -17942507
Locus: 8p22
MTUS1 Gene Summary
This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]
Gene Name: Microtubule Associated Scaffold Protein 1
Chromosome: CHR8: 17501302 -17658426
Locus: 8p22
Gene Diseases
The MTUS1 ASAH1 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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