MTRR-SLC30A5 Fusion FISH Probe
The MTRR-SLC30A5 Fusion FISH Probe is used to confirm a fusion of the MTRR and SLC30A5 genes. The fusion of the MTRR and SLC30A5 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MTRR-SLC30A5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-RERE | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-REOR | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-REGO | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-REGR | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-OROR | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-GORE | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-GROR | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| MTRR-SLC30A5-20-AQAQ | 20 (40 μL) | 200 μL |
|
MTRR Gene Summary
This gene encodes a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. This protein functions in the synthesis of methionine by regenerating methionine synthase to a functional state. Because methionine synthesis requires methyl-group transfer by a folate donor, activity of the encoded enzyme is important for folate metabolism and cellular methylation. Mutations in this gene can cause homocystinuria-megaloblastic anemia, cbl E type. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Name: 5-methyltetrahydrofolate-homocysteine Methyltransferase Reductase
Chromosome: CHR5: 7869216 -7901235
Locus: 5p15.31
SLC30A5 Gene Summary
This gene encodes a member of the SLC30A/ZnT family of zinc transporter proteins. ZnT proteins mediate both cellular zinc efflux and zinc sequestration into membrane-bound organelles. The encoded protein plays a role in the early secretory pathway as a heterodimer with zinc transporter 6, and may also regulate zinc sequestration into secretory granules of pancreatic beta cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19. [provided by RefSeq, Oct 2011]
Gene Name: Solute Carrier Family 30 Member 5
Chromosome: CHR5: 68389781 -68426899
Locus: 5q13.1-q13.2
Gene Diseases
The MTRR SLC30A5 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|