MTMR3-TSHZ2 Fusion FISH Probe
The MTMR3-TSHZ2 Fusion FISH Probe is used to confirm a fusion of the MTMR3 and TSHZ2 genes. The fusion of the MTMR3 and TSHZ2 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MTMR3-TSHZ2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-RERE | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-REOR | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-REGO | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-REGR | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-REAQ | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-ORRE | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-OROR | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-ORGO | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-ORAQ | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-GORE | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-GOOR | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-GOGO | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-GOGR | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-GOAQ | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-GRRE | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-GROR | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-GRGO | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-GRGR | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-GRAQ | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-AQRE | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-AQOR | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-AQGO | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-AQGR | 20 (40 μL) | 200 μL |
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| MTMR3-TSHZ2-20-AQAQ | 20 (40 μL) | 200 μL |
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MTMR3 Gene Summary
This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Myotubularin Related Protein 3
Chromosome: CHR22: 30279157 -30426857
Locus: 22q12.2
TSHZ2 Gene Summary
This gene is a member of the teashirt C2H2-type zinc-finger protein family of transcription factors. This gene encodes a protein with five C2H2-type zinc fingers, a homeobox DNA-binding domain and a coiled-coil domain. This nuclear protein is predicted to act as a transcriptional repressor. This gene is thought to play a role in the development and progression of breast and other types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
Gene Name: Teashirt Zinc Finger Homeobox 2
Chromosome: CHR20: 51588945 -52111869
Locus: 20q13.2
Gene Diseases
The MTMR3 TSHZ2 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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