MTMR3-CLIP2 Fusion FISH Probe
The MTMR3-CLIP2 Fusion FISH Probe is used to confirm a fusion of the MTMR3 and CLIP2 genes. The fusion of the MTMR3 and CLIP2 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MTMR3-CLIP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-RERE | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-REOR | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-REGO | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-REGR | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-REAQ | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-ORRE | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-OROR | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-ORGO | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-GORE | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-GOOR | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-GOGO | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-GOGR | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-GRRE | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-GROR | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-GRGO | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-GRGR | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-AQRE | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-AQOR | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-AQGO | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-AQGR | 20 (40 μL) | 200 μL |
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| MTMR3-CLIP2-20-AQAQ | 20 (40 μL) | 200 μL |
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CLIP2 Gene Summary
The protein encoded by this gene belongs to the family of cytoplasmic linker proteins, which have been proposed to mediate the interaction between specific membranous organelles and microtubules. This protein was found to associate with both microtubules and an organelle called the dendritic lamellar body. This gene is hemizygously deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]
Gene Name: CAP-Gly Domain Containing Linker Protein 2
Chromosome: CHR7: 73703804 -73820273
Locus: 7q11.23
MTMR3 Gene Summary
This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Myotubularin Related Protein 3
Chromosome: CHR22: 30279157 -30426857
Locus: 22q12.2
Gene Diseases
The MTMR3 CLIP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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