MTMR12-ZFR Fusion FISH Probe
The MTMR12-ZFR Fusion FISH Probe is used to confirm a fusion of the MTMR12 and ZFR genes. The fusion of the MTMR12 and ZFR genes has been associated with Lung Adenocarcinoma, and Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MTMR12-ZFR-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-RERE | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-REOR | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-REGO | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-REGR | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-REAQ | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-ORRE | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-OROR | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-ORGO | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-ORAQ | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-GORE | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-GOOR | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-GOGO | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-GOGR | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-GOAQ | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-GRRE | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-GROR | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-GRGO | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-GRGR | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-GRAQ | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-AQRE | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-AQOR | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-AQGO | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-AQGR | 20 (40 μL) | 200 μL |
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| MTMR12-ZFR-20-AQAQ | 20 (40 μL) | 200 μL |
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ZFR Gene Summary
This gene encodes an RNA-binding protein characterized by its DZF (domain associated with zinc fingers) domain. The encoded protein may play a role in the nucleocytoplasmic shuttling of another RNA-binding protein, Staufen homolog 2, in neurons. Expression of this gene is regulated through alternative polyadenylation that mediates differential microRNA targeting. Elevated expression of this gene has been observed in human patients with pancreatic cancer and knockdown of this gene may result in reduced viability and invasion of pancreatic cancer cells. [provided by RefSeq, Sep 2016]
Gene Name: Zinc Finger RNA Binding Protein
Chromosome: CHR5: 32354455 -32444844
Locus: 5p13.3
MTMR12 Gene Summary
Phosphatidylinositide 3-kinase-derived membrane-anchored phosphatidylinositides, such as phosphatidylinositol 3-phosphate (PtdIns(3)P), regulate diverse cellular processes. The protein encoded by this gene functions as an adaptor subunit in a complex with an active PtdIns(3)P 3-phosphatase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Gene Name: Myotubularin Related Protein 12
Chromosome: CHR5: 32227110 -32313114
Locus: 5p13.3
Gene Diseases
The MTMR12 ZFR Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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