MTHFD1L-THEMIS Fusion FISH Probe
The MTHFD1L-THEMIS Fusion FISH Probe is used to confirm a fusion of the MTHFD1L and THEMIS genes. The fusion of the MTHFD1L and THEMIS genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MTHFD1L-THEMIS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-RERE | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-REOR | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-REGO | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-REGR | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-REAQ | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-ORRE | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-OROR | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-ORGO | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-ORAQ | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-GORE | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-GOOR | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-GOGO | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-GOGR | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-GOAQ | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-GRRE | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-GROR | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-GRGO | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-GRGR | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-GRAQ | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-AQRE | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-AQOR | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-AQGO | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-AQGR | 20 (40 μL) | 200 μL |
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| MTHFD1L-THEMIS-20-AQAQ | 20 (40 μL) | 200 μL |
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MTHFD1L Gene Summary
The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011]
Gene Name: Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1 Like
Chromosome: CHR6: 151186814 -151423023
Locus: 6q25.1
THEMIS Gene Summary
This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Gene Name: Thymocyte Selection Associated
Chromosome: CHR6: 128029338 -128239776
Locus: 6q22.33
Gene Diseases
The MTHFD1L THEMIS Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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