MTF2-RPL5 Fusion FISH Probe
The MTF2-RPL5 Fusion FISH Probe is used to confirm a fusion of the MTF2 and RPL5 genes. The fusion of the MTF2 and RPL5 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MTF2-RPL5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-RERE | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-REOR | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-REGO | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-REGR | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-REAQ | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-ORRE | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-OROR | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-ORGO | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-ORAQ | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-GORE | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-GOOR | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-GOGO | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-GOGR | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-GOAQ | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-GRRE | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-GROR | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-GRGO | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-GRGR | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-GRAQ | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-AQRE | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-AQOR | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-AQGO | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-AQGR | 20 (40 μL) | 200 μL |
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| MTF2-RPL5-20-AQAQ | 20 (40 μL) | 200 μL |
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RPL5 Gene Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18P family of ribosomal proteins and component of the 60S subunit. The encoded protein binds 5S rRNA to form a stable complex called the 5S ribonucleoprotein particle (RNP), which is necessary for the transport of nonribosome-associated cytoplasmic 5S rRNA to the nucleolus for assembly into ribosomes. The encoded protein may also function to inhibit tumorigenesis through the activation of downstream tumor suppressors and the downregulation of oncoprotein expression. Mutations in this gene have been identified in patients with Diamond-Blackfan Anemia (DBA). This gene is co-transcribed with the small nucleolar RNA gene U21, which is located in its fifth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Mar 2017]
Gene Name: Ribosomal Protein L5
Chromosome: CHR1: 93297593 -93307481
Locus: 1p22.1
MTF2 Gene Summary
The Metal Response Element Binding Transcription Factor 2 (MTF2) gene is located on chr1 :93544791-93604638 at 1p22.1.
Gene Name: Metal Response Element Binding Transcription Factor 2
Chromosome: CHR1: 93544791 -93604638
Locus: 1p22.1
Gene Diseases
The MTF2 RPL5 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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