MTAP-POC1B Fusion FISH Probe
The MTAP-POC1B Fusion FISH Probe is used to confirm a fusion of the MTAP and POC1B genes. The fusion of the MTAP and POC1B genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MTAP-POC1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-RERE | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-REOR | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-REGO | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-REGR | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-REAQ | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-ORRE | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-OROR | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-ORGO | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-GORE | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-GOOR | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-GOGO | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-GOGR | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-GRRE | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-GROR | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-GRGO | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-GRGR | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-AQRE | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-AQOR | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-AQGO | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-AQGR | 20 (40 μL) | 200 μL |
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| MTAP-POC1B-20-AQAQ | 20 (40 μL) | 200 μL |
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MTAP Gene Summary
This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown. [provided by RefSeq, Jul 2008]
Gene Name: Methylthioadenosine Phosphorylase
Chromosome: CHR9: 21802634 -21865969
Locus: 9p21.3
POC1B Gene Summary
POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutation in this gene result in autosomal-recessive cone-rod dystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Gene Name: POC1 Centriolar Protein B
Chromosome: CHR12: 89813497 -89920039
Locus: 12q21.33
Gene Diseases
The MTAP POC1B Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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