MTAP-EXOC6B Fusion FISH Probe
The MTAP-EXOC6B Fusion FISH Probe is used to confirm a fusion of the MTAP and EXOC6B genes. The fusion of the MTAP and EXOC6B genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MTAP-EXOC6B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-RERE | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-REOR | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-REGO | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-REGR | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-REAQ | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-ORRE | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-OROR | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-ORGO | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-ORAQ | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-GORE | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-GOOR | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-GOGO | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-GOGR | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-GOAQ | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-GRRE | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-GROR | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-GRGO | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-GRGR | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-GRAQ | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-AQRE | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-AQOR | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-AQGO | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-AQGR | 20 (40 μL) | 200 μL |
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| MTAP-EXOC6B-20-AQAQ | 20 (40 μL) | 200 μL |
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MTAP Gene Summary
This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown. [provided by RefSeq, Jul 2008]
Gene Name: Methylthioadenosine Phosphorylase
Chromosome: CHR9: 21802634 -21865969
Locus: 9p21.3
EXOC6B Gene Summary
This gene encodes a protein which is a part of the evolutionarily conserved exocyst, a multimeric protein complex necessary for exocytosis, which in turn, is crucial for cell growth, polarity and migration. Disruption of this gene may be associated with phenotypes exhibiting multiple symptoms including intellectual disability and developmental delay (DD). [provided by RefSeq, Jun 2016]
Gene Name: Exocyst Complex Component 6B
Chromosome: CHR2: 72406443 -73053177
Locus: 2p13.2
Gene Diseases
The MTAP EXOC6B Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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