MSL2-OPRM1 Fusion FISH Probe
The MSL2-OPRM1 Fusion FISH Probe is used to confirm a fusion of the MSL2 and OPRM1 genes. The fusion of the MSL2 and OPRM1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MSL2-OPRM1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-RERE | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-REOR | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-REGO | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-REGR | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-REAQ | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-ORRE | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-OROR | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-ORGO | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-GORE | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-GOOR | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-GOGO | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-GOGR | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-GRRE | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-GROR | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-GRGO | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-GRGR | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-AQRE | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-AQOR | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-AQGO | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-AQGR | 20 (40 μL) | 200 μL |
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| MSL2-OPRM1-20-AQAQ | 20 (40 μL) | 200 μL |
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OPRM1 Gene Summary
This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains. [provided by RefSeq, Oct 2013]
Gene Name: Opioid Receptor Mu 1
Chromosome: CHR6: 154360442 -154568001
Locus: 6q25.2
MSL2 Gene Summary
The MSL Complex Subunit 2 (MSL2) gene is located on chr3 :135867759-135914688 at 3q22.3.
Gene Name: MSL Complex Subunit 2
Chromosome: CHR3: 135867759 -135914688
Locus: 3q22.3
Gene Diseases
The MSL2 OPRM1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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