MSI2-HNF1B Fusion FISH Probe
The MSI2-HNF1B Fusion FISH Probe is used to confirm a fusion of the MSI2 and HNF1B genes. The fusion of the MSI2 and HNF1B genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MSI2-HNF1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-RERE | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-REOR | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-REGO | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-REGR | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-REAQ | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-ORRE | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-OROR | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-ORGO | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-GORE | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-GOOR | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-GOGO | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-GOGR | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-GRRE | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-GROR | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-GRGO | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-GRGR | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-AQRE | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-AQOR | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-AQGO | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-AQGR | 20 (40 μL) | 200 μL |
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| MSI2-HNF1B-20-AQAQ | 20 (40 μL) | 200 μL |
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HNF1B Gene Summary
This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Gene Name: HNF1 Homeobox B
Chromosome: CHR17: 36046433 -36105096
Locus: 17q12
MSI2 Gene Summary
This gene encodes an RNA-binding protein that is a member of the Musashi protein family. The encoded protein is transcriptional regulator that targets genes involved in development and cell cycle regulation. Mutations in this gene are associated with poor prognosis in certain types of cancers. This gene has also been shown to be rearranged in certain cancer cells. [provided by RefSeq, Apr 2016]
Gene Name: Musashi RNA Binding Protein 2
Chromosome: CHR17: 55333930 -55757299
Locus: 17q22
Gene Diseases
The MSI2 HNF1B Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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