MSH2-TTC7A Fusion FISH Probe
The MSH2-TTC7A Fusion FISH Probe is used to confirm a fusion of the MSH2 and TTC7A genes. The fusion of the MSH2 and TTC7A genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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MSH2-TTC7A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-RERE | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-REOR | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-REGO | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-REGR | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-REAQ | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-ORRE | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-OROR | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-ORGO | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-ORAQ | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-GORE | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-GOOR | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-GOGO | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-GOGR | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-GOAQ | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-GRRE | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-GROR | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-GRGO | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-GRGR | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-GRAQ | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-AQRE | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-AQOR | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-AQGO | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-AQGR | 20 (40 μL) | 200 μL | ||
MSH2-TTC7A-20-AQAQ | 20 (40 μL) | 200 μL |
MSH2 Gene Summary
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Name: MutS Homolog 2
Chromosome: CHR2: 47630262 -47710360
Locus: 2p21-p16.3
TTC7A Gene Summary
This gene encodes a protein containing tetratricopeptide repeats. Mutations in this gene disrupt intestinal development and can cause early onset inflammatory bowel disease and intestinal atresia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Gene Name: Tetratricopeptide Repeat Domain 7A
Chromosome: CHR2: 47168312 -47303275
Locus: 2p21
Gene Diseases
The MSH2 TTC7A Fusion has been associated with the following diseases:
Disease Name |
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Prostate Adenocarcinoma |
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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