MSH2-CCDC57 Fusion FISH Probe
The MSH2-CCDC57 Fusion FISH Probe is used to confirm a fusion of the MSH2 and CCDC57 genes. The fusion of the MSH2 and CCDC57 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MSH2-CCDC57-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-RERE | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-REOR | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-REGO | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-REGR | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-REAQ | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-ORRE | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-OROR | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-ORGO | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-ORAQ | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-GORE | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-GOOR | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-GOGO | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-GOGR | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-GOAQ | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-GRRE | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-GROR | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-GRGO | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-GRGR | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-GRAQ | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-AQRE | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-AQOR | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-AQGO | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-AQGR | 20 (40 μL) | 200 μL |
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| MSH2-CCDC57-20-AQAQ | 20 (40 μL) | 200 μL |
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MSH2 Gene Summary
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Name: MutS Homolog 2
Chromosome: CHR2: 47630262 -47710360
Locus: 2p21-p16.3
CCDC57 Gene Summary
The Coiled-coil Domain Containing 57 (CCDC57) gene is located on chr17 :80059345-80170689 at 17q25.3.
Gene Name: Coiled-coil Domain Containing 57
Chromosome: CHR17: 80059345 -80170689
Locus: 17q25.3
Gene Diseases
The MSH2 CCDC57 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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