MRPS23-TRIM37 Fusion FISH Probe
The MRPS23-TRIM37 Fusion FISH Probe is used to confirm a fusion of the MRPS23 and TRIM37 genes. The fusion of the MRPS23 and TRIM37 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MRPS23-TRIM37-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-RERE | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-REOR | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-REGO | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-REGR | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-REAQ | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-ORRE | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-OROR | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-ORGO | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-ORAQ | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-GORE | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-GOOR | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-GOGO | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-GOGR | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-GOAQ | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-GRRE | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-GROR | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-GRGO | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-GRGR | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-GRAQ | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-AQRE | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-AQOR | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-AQGO | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-AQGR | 20 (40 μL) | 200 μL |
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| MRPS23-TRIM37-20-AQAQ | 20 (40 μL) | 200 μL |
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TRIM37 Gene Summary
This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. [provided by RefSeq, Mar 2016]
Gene Name: Tripartite Motif Containing 37
Chromosome: CHR17: 57059999 -57184266
Locus: 17q22
MRPS23 Gene Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 7p. [provided by RefSeq, Jul 2008]
Gene Name: Mitochondrial Ribosomal Protein S23
Chromosome: CHR17: 55916286 -55927433
Locus: 17q22
Gene Diseases
The MRPS23 TRIM37 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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