MRPS23-FAM117A Fusion FISH Probe
The MRPS23-FAM117A Fusion FISH Probe is used to confirm a fusion of the MRPS23 and FAM117A genes. The fusion of the MRPS23 and FAM117A genes has been associated with Sarcoma, and Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MRPS23-FAM117A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-RERE | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-REOR | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-REGO | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-REGR | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-REAQ | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-ORRE | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-OROR | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-ORGO | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-ORAQ | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-GORE | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-GOOR | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-GOGO | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-GOGR | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-GOAQ | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-GRRE | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-GROR | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-GRGO | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-GRGR | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-GRAQ | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-AQRE | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-AQOR | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-AQGO | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-AQGR | 20 (40 μL) | 200 μL |
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| MRPS23-FAM117A-20-AQAQ | 20 (40 μL) | 200 μL |
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MRPS23 Gene Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 7p. [provided by RefSeq, Jul 2008]
Gene Name: Mitochondrial Ribosomal Protein S23
Chromosome: CHR17: 55916286 -55927433
Locus: 17q22
FAM117A Gene Summary
The Family With Sequence Similarity 117 Member A (FAM117A) gene is located on chr17 :47787686-47841518 at 17q21.33.
Gene Name: Family With Sequence Similarity 117 Member A
Chromosome: CHR17: 47787686 -47841518
Locus: 17q21.33
Gene Diseases
The MRPS23 FAM117A Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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