MRPS22-SLC9A9 Fusion FISH Probe
The MRPS22-SLC9A9 Fusion FISH Probe is used to confirm a fusion of the MRPS22 and SLC9A9 genes. The fusion of the MRPS22 and SLC9A9 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MRPS22-SLC9A9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-RERE | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-REOR | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-REGO | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-REGR | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-REAQ | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-ORRE | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-OROR | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-ORGO | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-ORAQ | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-GORE | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-GOOR | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-GOGO | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-GOGR | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-GOAQ | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-GRRE | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-GROR | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-GRGO | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-GRGR | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-GRAQ | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-AQRE | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-AQOR | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-AQGO | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-AQGR | 20 (40 μL) | 200 μL |
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| MRPS22-SLC9A9-20-AQAQ | 20 (40 μL) | 200 μL |
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MRPS22 Gene Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. This gene lies telomeric of and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene corresponding to this gene is found on chromosome Xq. [provided by RefSeq, Jul 2008]
Gene Name: Mitochondrial Ribosomal Protein S22
Chromosome: CHR3: 139062860 -139075887
Locus: 3q23
SLC9A9 Gene Summary
This gene encodes a sodium/proton exchanger that is a member of the solute carrier 9 protein family. The encoded protein localizes the to the late recycling endosomes and may play an important role in maintaining cation homeostasis. Mutations in this gene are associated with autism susceptibility 16 and attention-deficit/hyperactivity disorder. [provided by RefSeq, Mar 2012]
Gene Name: Solute Carrier Family 9 Member A9
Chromosome: CHR3: 142984063 -143567373
Locus: 3q24
Gene Diseases
The MRPS22 SLC9A9 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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