MRPL40-TMCC3 Fusion FISH Probe
The MRPL40-TMCC3 Fusion FISH Probe is used to confirm a fusion of the MRPL40 and TMCC3 genes. The fusion of the MRPL40 and TMCC3 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MRPL40-TMCC3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-RERE | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-REOR | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-REGO | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-REGR | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-REAQ | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-ORRE | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-OROR | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-ORGO | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-ORAQ | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-GORE | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-GOOR | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-GOGO | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-GOGR | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-GOAQ | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-GRRE | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-GROR | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-GRGO | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-GRGR | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-GRAQ | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-AQRE | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-AQOR | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-AQGO | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-AQGR | 20 (40 μL) | 200 μL |
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| MRPL40-TMCC3-20-AQAQ | 20 (40 μL) | 200 μL |
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TMCC3 Gene Summary
The Transmembrane And Coiled-coil Domain Family 3 (TMCC3) gene is located on chr12 :94960899-95044324 at 12q22.
Gene Name: Transmembrane And Coiled-coil Domain Family 3
Chromosome: CHR12: 94960899 -95044324
Locus: 12q22
MRPL40 Gene Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome. [provided by RefSeq, Jul 2008]
Gene Name: Mitochondrial Ribosomal Protein L40
Chromosome: CHR22: 19420035 -19423596
Locus: 22q11.21
Gene Diseases
The MRPL40 TMCC3 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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