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MRPL11-ST8SIA1 Fusion FISH Probe

The MRPL11-ST8SIA1 Fusion FISH Probe is used to confirm a fusion of the MRPL11 and ST8SIA1 genes. The fusion of the MRPL11 and ST8SIA1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MRPL11-ST8SIA1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-RERE 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-REOR 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-REGO 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-REGR 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-REAQ 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-ORRE 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-OROR 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-ORGO 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-ORAQ 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-GORE 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-GOOR 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-GOGO 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-GOGR 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-GOAQ 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-GRRE 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-GROR 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-GRGO 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-GRGR 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-GRAQ 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-AQRE 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-AQOR 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-AQGO 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-AQGR 20 (40 μL) 200 μL
MRPL11-ST8SIA1-20-AQAQ 20 (40 μL) 200 μL

ST8SIA1 Gene Summary

Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2015]

Gene Name: ST8 Alpha-N-acetyl-neuraminide Alpha-2,8-sialyltransferase 1

Chromosome: CHR12: 22346324 -22487648

Locus: 12p12.1

MRPL11 Gene Summary

This nuclear gene encodes a 39S subunit component of the mitochondial ribosome. Alternative splicing results in multiple transcript variants. Pseudogenes for this gene are found on chromosomes 5 and 12. [provided by RefSeq, May 2014]

Gene Name: Mitochondrial Ribosomal Protein L11

Chromosome: CHR11: 66202549 -66206310

Locus: 11q13.2

Gene Diseases

The MRPL11 ST8SIA1 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.