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MREG-SPAG17 Fusion FISH Probe

The MREG-SPAG17 Fusion FISH Probe is used to confirm a fusion of the MREG and SPAG17 genes. The fusion of the MREG and SPAG17 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MREG-SPAG17-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MREG-SPAG17-20-RERE 20 (40 μL) 200 μL
MREG-SPAG17-20-REOR 20 (40 μL) 200 μL
MREG-SPAG17-20-REGO 20 (40 μL) 200 μL
MREG-SPAG17-20-REGR 20 (40 μL) 200 μL
MREG-SPAG17-20-REAQ 20 (40 μL) 200 μL
MREG-SPAG17-20-ORRE 20 (40 μL) 200 μL
MREG-SPAG17-20-OROR 20 (40 μL) 200 μL
MREG-SPAG17-20-ORGO 20 (40 μL) 200 μL
MREG-SPAG17-20-ORAQ 20 (40 μL) 200 μL
MREG-SPAG17-20-GORE 20 (40 μL) 200 μL
MREG-SPAG17-20-GOOR 20 (40 μL) 200 μL
MREG-SPAG17-20-GOGO 20 (40 μL) 200 μL
MREG-SPAG17-20-GOGR 20 (40 μL) 200 μL
MREG-SPAG17-20-GOAQ 20 (40 μL) 200 μL
MREG-SPAG17-20-GRRE 20 (40 μL) 200 μL
MREG-SPAG17-20-GROR 20 (40 μL) 200 μL
MREG-SPAG17-20-GRGO 20 (40 μL) 200 μL
MREG-SPAG17-20-GRGR 20 (40 μL) 200 μL
MREG-SPAG17-20-GRAQ 20 (40 μL) 200 μL
MREG-SPAG17-20-AQRE 20 (40 μL) 200 μL
MREG-SPAG17-20-AQOR 20 (40 μL) 200 μL
MREG-SPAG17-20-AQGO 20 (40 μL) 200 μL
MREG-SPAG17-20-AQGR 20 (40 μL) 200 μL
MREG-SPAG17-20-AQAQ 20 (40 μL) 200 μL

MREG Gene Summary

The Melanoregulin (MREG) gene is located on chr2 :216807313-216878346 at 2q35.

Gene Name: Melanoregulin

Chromosome: CHR2: 216807313 -216878346

Locus: 2q35

SPAG17 Gene Summary

This gene encodes a central pair protein present in the axonemes of cells with a "9 + 2" organization of microtubules. The encoded protein is required for the proper function of the axoneme. Mutations in the orthologous gene in mice lead to primary ciliary dyskinesia characterized by immotile nasal and tracheal cilia, reduced clearance of nasal mucus, profound respiratory distress, hydrocephalus, and neonatal lethality within twelve hours of birth due to impaired airway mucociliary clearance. Single-nucleotide polymorphisms in this gene are associated with human height and targeted mutations lead to skeletal malformations affecting the limbs in mice, suggesting a role for this gene in skeletal development. [provided by RefSeq, Feb 2017]

Gene Name: Sperm Associated Antigen 17

Chromosome: CHR1: 118496287 -118727848

Locus: 1p12

Gene Diseases

The MREG SPAG17 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.