MPRIP-COPS3 Fusion FISH Probe
The MPRIP-COPS3 Fusion FISH Probe is used to confirm a fusion of the MPRIP and COPS3 genes. The fusion of the MPRIP and COPS3 genes has been associated with Kidney Renal Papillary Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MPRIP-COPS3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-RERE | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-REOR | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-REGO | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-REGR | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-OROR | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-GORE | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-GROR | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| MPRIP-COPS3-20-AQAQ | 20 (40 μL) | 200 μL |
|
COPS3 Gene Summary
The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Gene Name: COP9 Signalosome Subunit 3
Chromosome: CHR17: 17149937 -17184617
Locus: 17p11.2
MPRIP Gene Summary
The Myosin Phosphatase Rho Interacting Protein (MPRIP) gene is located on chr17 :16946073-17095962 at 17p11.2.
Gene Name: Myosin Phosphatase Rho Interacting Protein
Chromosome: CHR17: 16946073 -17095962
Locus: 17p11.2
Gene Diseases
The MPRIP COPS3 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Kidney Renal Papillary Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|