MOSC1-VPS33A Fusion FISH Probe
The MOSC1-VPS33A Fusion FISH Probe is used to confirm a fusion of the MOSC1 and VPS33A genes. The fusion of the MOSC1 and VPS33A genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MOSC1-VPS33A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-RERE | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-REOR | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-REGO | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-REGR | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-REAQ | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-ORRE | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-OROR | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-ORGO | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-ORAQ | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-GORE | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-GOOR | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-GOGO | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-GOGR | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-GOAQ | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-GRRE | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-GROR | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-GRGO | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-GRGR | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-GRAQ | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-AQRE | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-AQOR | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-AQGO | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-AQGR | 20 (40 μL) | 200 μL |
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| MOSC1-VPS33A-20-AQAQ | 20 (40 μL) | 200 μL |
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VPS33A Gene Summary
This gene encodes a tethering protein and a core subunit of the homotypic fusion and protein sorting (HOPS) complex. The HOPS complex and a second endosomal tethering complex called the class C core vacuole/endosome tethering (CORVET) complex, perform diverse functions in endocytosis including membrane tethering, RabGTPase interaction, activation and proofreading of synaptic-soluble N-ethylmaleimide-sensitive factor attachment receptor (SNARE) assembly to drive membrane fusion, and endosome-to-cytoskeleton attachment. The HOPS complex controls endosome maturation as well as endosome traffic to the lysosome. This complex is essential for vacuolar fusion and is required for adaptor protein complex 3-dependent transport from the golgi to the vacuole. The encoded protein belongs to the Sec1/Munc18 (SM) family of SNARE-mediated membrane fusion regulators. Naturally occurring mutations in this gene are associated with a novel mucopolysaccharidosis-like disease. [provided by RefSeq, Apr 2017]
Gene Name: VPS33A, CORVET/HOPS Core Subunit
Chromosome: CHR12: 122716093 -122751068
Locus: 12q24.31
Gene Diseases
The MOSC1 VPS33A Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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