MNAT1-SIX1 Fusion FISH Probe
The MNAT1-SIX1 Fusion FISH Probe is used to confirm a fusion of the MNAT1 and SIX1 genes. The fusion of the MNAT1 and SIX1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MNAT1-SIX1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-RERE | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-REOR | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-REGO | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-REGR | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-REAQ | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-ORRE | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-OROR | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-ORGO | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-GORE | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-GOOR | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-GOGO | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-GOGR | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-GRRE | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-GROR | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-GRGO | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-GRGR | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-AQRE | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-AQOR | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-AQGO | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-AQGR | 20 (40 μL) | 200 μL |
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| MNAT1-SIX1-20-AQAQ | 20 (40 μL) | 200 μL |
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MNAT1 Gene Summary
The protein encoded by this gene, along with cyclin H and CDK7, forms the CDK-activating kinase (CAK) enzymatic complex. This complex activates several cyclin-associated kinases and can also associate with TFIIH to activate transcription by RNA polymerase II. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Name: MNAT1, CDK Activating Kinase Assembly Factor
Chromosome: CHR14: 61201458 -61435398
Locus: 14q23.1
SIX1 Gene Summary
The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in limb development. Defects in this gene are a cause of autosomal dominant deafness type 23 (DFNA23) and branchiootic syndrome type 3 (BOS3). [provided by RefSeq, Jul 2008]
Gene Name: SIX Homeobox 1
Chromosome: CHR14: 61111416 -61116155
Locus: 14q23.1
Gene Diseases
The MNAT1 SIX1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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