MMP28-KCNJ12 Fusion FISH Probe
The MMP28-KCNJ12 Fusion FISH Probe is used to confirm a fusion of the MMP28 and KCNJ12 genes. The fusion of the MMP28 and KCNJ12 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MMP28-KCNJ12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-RERE | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-REOR | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-REGO | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-REGR | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-REAQ | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-ORRE | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-OROR | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-ORGO | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-ORAQ | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-GORE | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-GOOR | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-GOGO | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-GOGR | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-GOAQ | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-GRRE | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-GROR | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-GRGO | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-GRGR | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-GRAQ | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-AQRE | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-AQOR | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-AQGO | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-AQGR | 20 (40 μL) | 200 μL |
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| MMP28-KCNJ12-20-AQAQ | 20 (40 μL) | 200 μL |
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KCNJ12 Gene Summary
This gene encodes an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current (IK1). The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
Gene Name: Potassium Voltage-gated Channel Subfamily J Member 12
Chromosome: CHR17: 21279698 -21323179
Locus: 17p11.2
MMP28 Gene Summary
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. This gene encodes a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Gene Name: Matrix Metallopeptidase 28
Chromosome: CHR17: 34092875 -34122640
Locus: 17q12
Gene Diseases
The MMP28 KCNJ12 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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