MMD-APPBP2 Fusion FISH Probe
The MMD-APPBP2 Fusion FISH Probe is used to confirm a fusion of the MMD and APPBP2 genes. The fusion of the MMD and APPBP2 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MMD-APPBP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-RERE | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-REOR | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-REGO | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-REGR | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-REAQ | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-ORRE | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-OROR | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-ORGO | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-GORE | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-GOOR | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-GOGO | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-GOGR | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-GRRE | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-GROR | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-GRGO | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-GRGR | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-AQRE | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-AQOR | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-AQGO | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-AQGR | 20 (40 μL) | 200 μL |
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| MMD-APPBP2-20-AQAQ | 20 (40 μL) | 200 μL |
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APPBP2 Gene Summary
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Name: Amyloid Beta Precursor Protein Binding Protein 2
Chromosome: CHR17: 58520519 -58603580
Locus: 17q23.2
MMD Gene Summary
This protein is expressed by in vitro differentiated macrophages but not freshly isolated monocytes. Although sequence analysis identifies seven potential transmembrane domains, this protein has little homology to G-protein receptors and it has not been positively identified as a receptor. A suggested alternative function is that of an ion channel protein in maturing macrophages. [provided by RefSeq, Jul 2008]
Gene Name: Monocyte To Macrophage Differentiation Associated
Chromosome: CHR17: 53469973 -53499341
Locus: 17q22
Gene Diseases
The MMD APPBP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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