MLXIP-TSPAN8 Fusion FISH Probe
The MLXIP-TSPAN8 Fusion FISH Probe is used to confirm a fusion of the MLXIP and TSPAN8 genes. The fusion of the MLXIP and TSPAN8 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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MLXIP-TSPAN8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-RERE | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-REOR | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-REGO | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-REGR | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-REAQ | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-ORRE | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-OROR | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-ORGO | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-ORAQ | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-GORE | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-GOOR | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-GOGO | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-GOGR | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-GOAQ | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-GRRE | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-GROR | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-GRGO | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-GRGR | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-GRAQ | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-AQRE | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-AQOR | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-AQGO | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-AQGR | 20 (40 μL) | 200 μL | ||
MLXIP-TSPAN8-20-AQAQ | 20 (40 μL) | 200 μL |
TSPAN8 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Tetraspanin 8
Chromosome: CHR12: 71518876 -71551779
Locus: 12q21.1
MLXIP Gene Summary
This gene encodes a protein that functions as part of a heterodimer to activate transcription. The encoded protein forms a heterodimer with Max-like protein X (MLX) and is involved in the regulation of genes in response to cellular glucose levels. [provided by RefSeq, Mar 2014]
Gene Name: MLX Interacting Protein
Chromosome: CHR12: 122516759 -122628967
Locus: 12q24.31
Gene Diseases
The MLXIP TSPAN8 Fusion has been associated with the following diseases:
Disease Name |
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Sarcoma |
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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