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MLLT6-AATF Fusion FISH Probe

The MLLT6-AATF Fusion FISH Probe is used to confirm a fusion of the MLLT6 and AATF genes. The fusion of the MLLT6 and AATF genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MLLT6-AATF-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MLLT6-AATF-20-RERE 20 (40 μL) 200 μL
MLLT6-AATF-20-REOR 20 (40 μL) 200 μL
MLLT6-AATF-20-REGO 20 (40 μL) 200 μL
MLLT6-AATF-20-REGR 20 (40 μL) 200 μL
MLLT6-AATF-20-REAQ 20 (40 μL) 200 μL
MLLT6-AATF-20-ORRE 20 (40 μL) 200 μL
MLLT6-AATF-20-OROR 20 (40 μL) 200 μL
MLLT6-AATF-20-ORGO 20 (40 μL) 200 μL
MLLT6-AATF-20-ORAQ 20 (40 μL) 200 μL
MLLT6-AATF-20-GORE 20 (40 μL) 200 μL
MLLT6-AATF-20-GOOR 20 (40 μL) 200 μL
MLLT6-AATF-20-GOGO 20 (40 μL) 200 μL
MLLT6-AATF-20-GOGR 20 (40 μL) 200 μL
MLLT6-AATF-20-GOAQ 20 (40 μL) 200 μL
MLLT6-AATF-20-GRRE 20 (40 μL) 200 μL
MLLT6-AATF-20-GROR 20 (40 μL) 200 μL
MLLT6-AATF-20-GRGO 20 (40 μL) 200 μL
MLLT6-AATF-20-GRGR 20 (40 μL) 200 μL
MLLT6-AATF-20-GRAQ 20 (40 μL) 200 μL
MLLT6-AATF-20-AQRE 20 (40 μL) 200 μL
MLLT6-AATF-20-AQOR 20 (40 μL) 200 μL
MLLT6-AATF-20-AQGO 20 (40 μL) 200 μL
MLLT6-AATF-20-AQGR 20 (40 μL) 200 μL
MLLT6-AATF-20-AQAQ 20 (40 μL) 200 μL

MLLT6 Gene Summary

The MLLT6, PHD Finger Containing (MLLT6) gene is located on chr17 :36861872-36886056 at 17q12.

Gene Name: MLLT6, PHD Finger Containing

Chromosome: CHR17: 36861872 -36886056

Locus: 17q12

AATF Gene Summary

The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq, Jul 2008]

Gene Name: Apoptosis Antagonizing Transcription Factor

Chromosome: CHR17: 35306174 -35414171

Locus: 17q12

Gene Diseases

The MLLT6 AATF Fusion has been associated with the following diseases:

Disease Name
Kidney Renal Clear Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.