MLLT10-WAC Fusion FISH Probe
The MLLT10-WAC Fusion FISH Probe is used to confirm a fusion of the MLLT10 and WAC genes. The fusion of the MLLT10 and WAC genes has been associated with Brain Lower Grade Glioma, and Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MLLT10-WAC-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-RERE | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-REOR | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-REGO | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-REGR | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-REAQ | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-ORRE | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-OROR | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-ORGO | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-ORAQ | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-GORE | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-GOOR | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-GOGO | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-GOGR | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-GOAQ | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-GRRE | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-GROR | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-GRGO | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-GRGR | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-GRAQ | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-AQRE | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-AQOR | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-AQGO | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-AQGR | 20 (40 μL) | 200 μL |
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| MLLT10-WAC-20-AQAQ | 20 (40 μL) | 200 μL |
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MLLT10 Gene Summary
This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]
Gene Name: MLLT10, Histone Lysine Methyltransferase DOT1L Cofactor
Chromosome: CHR10: 21823100 -22032559
Locus: 10p12.31
WAC Gene Summary
The protein encoded by this gene contains a WW domain, which is a protein module found in a wide range of signaling proteins. This domain mediates protein-protein interactions and binds proteins containing short linear peptide motifs that are proline-rich or contain at least one proline. This gene product shares 94% sequence identity with the WAC protein in mouse, however, its exact function is not known. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
Gene Name: WW Domain Containing Adaptor With Coiled-coil
Chromosome: CHR10: 28821421 -28912041
Locus: 10p12.1-p11.2
Gene Diseases
The MLLT10 WAC Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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