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MLLT10-MINPP1 Fusion FISH Probe

The MLLT10-MINPP1 Fusion FISH Probe is used to confirm a fusion of the MLLT10 and MINPP1 genes. The fusion of the MLLT10 and MINPP1 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MLLT10-MINPP1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MLLT10-MINPP1-20-RERE 20 (40 μL) 200 μL
MLLT10-MINPP1-20-REOR 20 (40 μL) 200 μL
MLLT10-MINPP1-20-REGO 20 (40 μL) 200 μL
MLLT10-MINPP1-20-REGR 20 (40 μL) 200 μL
MLLT10-MINPP1-20-REAQ 20 (40 μL) 200 μL
MLLT10-MINPP1-20-ORRE 20 (40 μL) 200 μL
MLLT10-MINPP1-20-OROR 20 (40 μL) 200 μL
MLLT10-MINPP1-20-ORGO 20 (40 μL) 200 μL
MLLT10-MINPP1-20-ORAQ 20 (40 μL) 200 μL
MLLT10-MINPP1-20-GORE 20 (40 μL) 200 μL
MLLT10-MINPP1-20-GOOR 20 (40 μL) 200 μL
MLLT10-MINPP1-20-GOGO 20 (40 μL) 200 μL
MLLT10-MINPP1-20-GOGR 20 (40 μL) 200 μL
MLLT10-MINPP1-20-GOAQ 20 (40 μL) 200 μL
MLLT10-MINPP1-20-GRRE 20 (40 μL) 200 μL
MLLT10-MINPP1-20-GROR 20 (40 μL) 200 μL
MLLT10-MINPP1-20-GRGO 20 (40 μL) 200 μL
MLLT10-MINPP1-20-GRGR 20 (40 μL) 200 μL
MLLT10-MINPP1-20-GRAQ 20 (40 μL) 200 μL
MLLT10-MINPP1-20-AQRE 20 (40 μL) 200 μL
MLLT10-MINPP1-20-AQOR 20 (40 μL) 200 μL
MLLT10-MINPP1-20-AQGO 20 (40 μL) 200 μL
MLLT10-MINPP1-20-AQGR 20 (40 μL) 200 μL
MLLT10-MINPP1-20-AQAQ 20 (40 μL) 200 μL

MLLT10 Gene Summary

This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]

Gene Name: MLLT10, Histone Lysine Methyltransferase DOT1L Cofactor

Chromosome: CHR10: 21823100 -22032559

Locus: 10p12.31

MINPP1 Gene Summary

This gene encodes multiple inositol polyphosphate phosphatase; an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate; an activity formerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway.[provided by RefSeq, Sep 2009]

Gene Name: Multiple Inositol-polyphosphate Phosphatase 1

Chromosome: CHR10: 89264222 -89313218

Locus: 10q23.2

Gene Diseases

The MLLT10 MINPP1 Fusion has been associated with the following diseases:

Disease Name
Liver Hepatocellular Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.