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MLLT10-KCNJ6 Fusion FISH Probe

The MLLT10-KCNJ6 Fusion FISH Probe is used to confirm a fusion of the MLLT10 and KCNJ6 genes. The fusion of the MLLT10 and KCNJ6 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MLLT10-KCNJ6-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-RERE 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-REOR 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-REGO 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-REGR 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-REAQ 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-ORRE 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-OROR 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-ORGO 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-ORAQ 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-GORE 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-GOOR 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-GOGO 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-GOGR 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-GOAQ 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-GRRE 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-GROR 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-GRGO 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-GRGR 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-GRAQ 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-AQRE 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-AQOR 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-AQGO 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-AQGR 20 (40 μL) 200 μL
MLLT10-KCNJ6-20-AQAQ 20 (40 μL) 200 μL

KCNJ6 Gene Summary

This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability. [provided by RefSeq, Apr 2015]

Gene Name: Potassium Voltage-gated Channel Subfamily J Member 6

Chromosome: CHR21: 38996785 -39288696

Locus: 21q22.13

MLLT10 Gene Summary

This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]

Gene Name: MLLT10, Histone Lysine Methyltransferase DOT1L Cofactor

Chromosome: CHR10: 21823100 -22032559

Locus: 10p12.31

Gene Diseases

The MLLT10 KCNJ6 Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.