MLL3-SYTL5 Fusion FISH Probe
The MLL3-SYTL5 Fusion FISH Probe is used to confirm a fusion of the MLL3 and SYTL5 genes. The fusion of the MLL3 and SYTL5 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MLL3-SYTL5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-RERE | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-REOR | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-REGO | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-REGR | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-REAQ | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-ORRE | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-OROR | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-ORGO | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-ORAQ | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-GORE | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-GOOR | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-GOGO | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-GOGR | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-GOAQ | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-GRRE | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-GROR | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-GRGO | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-GRGR | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-GRAQ | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-AQRE | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-AQOR | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-AQGO | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-AQGR | 20 (40 μL) | 200 μL |
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| MLL3-SYTL5-20-AQAQ | 20 (40 μL) | 200 μL |
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SYTL5 Gene Summary
The protein encoded by this gene belongs to the synaptotagmin-like (Slp) protein family, which contains a unique homology domain at the N-terminus, referred to as the Slp homology domain (SHD). The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of this gene is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Gene Name: Synaptotagmin Like 5
Chromosome: CHRX: 37865834 -37988073
Locus: Xp11.4
Gene Diseases
The MLL3 SYTL5 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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