MLEC-STX2 Fusion FISH Probe
The MLEC-STX2 Fusion FISH Probe is used to confirm a fusion of the MLEC and STX2 genes. The fusion of the MLEC and STX2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MLEC-STX2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| MLEC-STX2-20-AQAQ | 20 (40 μL) | 200 μL |
|
STX2 Gene Summary
The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Syntaxin 2
Chromosome: CHR12: 131274146 -131323811
Locus: 12q24.33
MLEC Gene Summary
This gene encodes the carbohydrate-binding protein malectin which is a Type I membrane-anchored endoplasmic reticulum protein. This protein has an affinity for Glc2Man9GlcNAc2 (G2M9) N-glycans and is involved in regulating glycosylation in the endoplasmic reticulum. This protein has also been shown to interact with ribophorin I and may be involved in the directing the degradation of misfolded proteins. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Gene Name: Malectin
Chromosome: CHR12: 121124948 -121139667
Locus: 12q24.31
Gene Diseases
The MLEC STX2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|