MKLN1-IMMP2L Fusion FISH Probe
The MKLN1-IMMP2L Fusion FISH Probe is used to confirm a fusion of the MKLN1 and IMMP2L genes. The fusion of the MKLN1 and IMMP2L genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MKLN1-IMMP2L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-RERE | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-REOR | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-REGO | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-REGR | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-REAQ | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-ORRE | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-OROR | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-ORGO | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-ORAQ | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-GORE | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-GOOR | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-GOGO | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-GOGR | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-GOAQ | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-GRRE | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-GROR | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-GRGO | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-GRGR | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-GRAQ | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-AQRE | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-AQOR | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-AQGO | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-AQGR | 20 (40 μL) | 200 μL |
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| MKLN1-IMMP2L-20-AQAQ | 20 (40 μL) | 200 μL |
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MKLN1 Gene Summary
Muskelin is an intracellular protein that acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component thrombospondin I (MIM 188060) (Adams et al., 1998 [PubMed 9724633]).[supplied by OMIM, Mar 2008]
Gene Name: Muskelin 1
Chromosome: CHR7: 130794854 -131181398
Locus: 7q32.3
IMMP2L Gene Summary
This gene encodes a protein involved in processing the signal peptide sequences used to direct mitochondrial proteins to the mitochondria. The encoded protein resides in the mitochondria and is one of the necessary proteins for the catalytic activity of the mitochondrial inner membrane peptidase (IMP) complex. Two variants that encode the same protein have been described for this gene. [provided by RefSeq, Sep 2011]
Gene Name: Inner Mitochondrial Membrane Peptidase Subunit 2
Chromosome: CHR7: 110303109 -111202347
Locus: 7q31.1
Gene Diseases
The MKLN1 IMMP2L Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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