MKLN1-CDK14 Fusion FISH Probe
The MKLN1-CDK14 Fusion FISH Probe is used to confirm a fusion of the MKLN1 and CDK14 genes. The fusion of the MKLN1 and CDK14 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MKLN1-CDK14-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-RERE | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-REOR | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-REGO | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-REGR | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-REAQ | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-ORRE | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-OROR | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-ORGO | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-ORAQ | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-GORE | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-GOOR | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-GOGO | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-GOGR | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-GOAQ | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-GRRE | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-GROR | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-GRGO | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-GRGR | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-GRAQ | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-AQRE | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-AQOR | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-AQGO | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-AQGR | 20 (40 μL) | 200 μL |
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| MKLN1-CDK14-20-AQAQ | 20 (40 μL) | 200 μL |
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MKLN1 Gene Summary
Muskelin is an intracellular protein that acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component thrombospondin I (MIM 188060) (Adams et al., 1998 [PubMed 9724633]).[supplied by OMIM, Mar 2008]
Gene Name: Muskelin 1
Chromosome: CHR7: 130794854 -131181398
Locus: 7q32.3
CDK14 Gene Summary
PFTK1 is a member of the CDC2 (MIM 116940)-related protein kinase family (Yang and Chen, 2001 [PubMed 11313143]).[supplied by OMIM, Mar 2008]
Gene Name: Cyclin Dependent Kinase 14
Chromosome: CHR7: 90338711 -90839904
Locus: 7q21.13
Gene Diseases
The MKLN1 CDK14 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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